Sublingual sufentanil approved despite controversy, concerns

Nebraska Economy Grows Despite Recession Concerns

Quebec stands firm on asbestos exports despite growing controversy.

Premier of Quebec Jean Charest is refusing to stop exporting chrysotile asbestos, despite a growing international outcry accusing Canada of hypocrisy in promoting the sale of a known carcinogen. On a trade mission in February to India — the largest buyer of asbestos from Quebec — protests greeted Charest at two of his stops, including a summit on sustainable development in Delhi. Members of the...

Between evidence and commerce – the case of sufentanil sublingual tablet systems

Sufentanil Sublingual Tablet System for the Management of Postoperative Pain Following Open Abdominal Surgery

BACKGROUND AND OBJECTIVES This study evaluates the efficacy and safety of a sufentanil sublingual tablet system (SSTS) for the management of postoperative pain following open abdominal surgery. METHODS At 13 hospital sites in the United States, patients following surgery with pain intensity of greater than 4 on an 11-point numerical rating scale were randomized to receive SSTS dispensing a 15...

A dose-finding study of sufentanil sublingual microtablets for the management of postoperative bunionectomy pain.

BACKGROUND Sufentanil sublingual microtablets (SSMs) at a dose of 15 µg per tablet have been studied for postoperative patient-controlled analgesia with a 20-minute lockout via a bedside handheld system over 2 days to 3 days of use. For more short-term (<24 hours) management of acute moderate-to-severe pain, such as in the ambulatory surgical setting, a single, higher-strength SSM dose administ...